4th Translational Genomics & Epigenomics Symposium
September 19 & 20, 2024
2016 SCHEDULE
FRIDAY, SEPTEMBER 23, 2016
Hohn Auditorium, Research Study Center, Roswell Park Cancer Institute
​8:00am
Registration - Breakfast
​8:45 - 9:00am
Welcome Remarks
Candace Johnson, PhD, CEO, Roswell Park Cancer Institute
SESSION I
METHYLATION AND HISTONE MODIFICATION
Session Chair: Dominic Smiraglia, PhD
Department Cancer Genetics, Roswell Park Cancer Institute
​9:00 - 9:05am
Session Introduction
​9:05 - 9:35am
Cis-acting control of DNA methylation
Paul Soloway, PhD, Cornell University
9:35 - 10:05am
Translocation Associated Sarcomas: Reprogramming the Cancer Epigenome
Joyce Ohm, PhD, Roswell Park Cancer Institute
10:05 - 10:35am
Control of cell differentiation by 5-hydroxymethylcytosine
Lucy Godley, MD, PhD, University of Chicago
​10:35 - 10:50am
DNA methylation profile in lungs of smokers and patients with COPD is associated with specific genes and cellular pathways
Isaac Sundar, University of Rochester
​10:50 - 11:00am
BREAK
​11:00 - 11:10am
Keyonote Speaker Introduction
Anna Woloszynska-Read, PhD, Roswell Park Cancer Institute
11:10 - 12:00pm
Transcriptional dynamics in epigenetic plasticity: implications for cancer biology and therapy
Paula Vertino, PhD, Emory University
KEYNOTE
12:00 - 1:30pm
LUNCH
POSTER SESSION
Gaylord Cary room
​
-- opportunity to do a guided walking tour around campus organized by BNMC --
SESSION II
INTEGRATIVE GENOMICS
Session Chair: Irwin Gelman, PhD
Department of Cancer Genetics, Roswell Park Cancer Institute
1:30 - 1:35pm
Session Introduction
​1:35 - 2:05pm
Dissecting molecular mechanisms of transcription regulation in vivo using genome-wide strategies
John Lis, PhD, Cornell University
2:05 - 2:35pm
DNA variations at regulatory elements
Tao Liu (SUNY University at Buffalo)
2:35 - 3:05pm
The hitherto unknown RNA editing activity of APOBEC proteins
Santosh Patnaik, MD, PhD, Roswell Park Cancer Institute
3:05 - 3:20pm
Molecular dissection of the oncogenic role of ETS1 in basal subtypes of breast cancer
Christian Gluck, University of Buffalo
​3:20 - 3:40pm
BREAK
​3:40 - 3:50am
Keyonote Speaker Introduction
Michael Buck, PhD, SUNY University at Buffalo
3:50 - 4:40pm
Precision medicine: forgetting the germ line?
Charis Eng, PhD, Cleveland Clinic
KEYNOTE
4:40 - 6:00pm
SOCIAL GATHERING/POSTER SESSION, co-sponsored by RPCI and BNMC
Gaylord Cary room
SATURDAY, SEPTEMBER 24, 2016
Hohn Auditorium, Research Study Center, Roswell Park Cancer Institute
​8:00am
Registration - Breakfast
SESSION III
EPIGENOMICS THERAPY AND BIOMARKERS
Session Chair: James Jarvis, MD, Department of Pediatrics, SUNY University at Buffalo
​9:00 - 9:05am
Session Introduction
​9:05 - 9:35am
Epigenetics and the heart of malignancy
Yogen Saunthararajah, MD, Cleveland Clinic
9:35 - 10:05am
Arsenic, a genotoxic and/or epigenotoxic carcinogen?
Xuefeng Ren, MD, PhD, SUNY University at Buffalo
10:05 - 10:35am
Epigenomics in population studies to understand cancer etiology
Christine Ambrosone, PhD, Roswell Park Cancer Institute
​10:35 - 10:50am
Chromatin disruption with small molecule as a novel type of anti-cancer therapy
Katerina Gurova, PhD, Roswell Park Cancer Institute
​10:50 - 11:00am
BREAK
​11:00 - 11:10am
Keyonote Speaker Introduction
Prashant Singh, PhD, Roswell Park Cancer Institute
KEYNOTE
11:10 - 12:00pm
DNA Methylation as a Biomarker and Therapeutic Target in Cancer
David De Carvalho, PhD, Ontario Cancer Institute, Princess Margaret Hospital
12:00 - 1:30pm
LUNCH
POSTER SESSION
Gaylord Cary room
SESSION IV
CLINICAL GENOMICS
Session Chair: Norma Nowak, PhD
Department of Biochemistry, SUNY University at Buffalo
1:30 - 1:35pm
Session Introduction
​1:35 - 2:05pm
A rational for targeting common features of cancer cells
Hartmut K. Land, PhD, University of Rochester
2:05 - 2:35pm
Precision medicine trials in oncology
Carl Morrison, MD, DVM, OmniSeq
2:35 - 3:05pm
Leveraging clinical genomics to enable personalized medicine prostate and multiple myeloma case studies
John Rushton, PhD, Empire Genomics
3:05 - 3:20pm
Off-target analysis of RNAI screens identifies microRNA contributing to metastatic invasion
Henry Withers, Roswell Park Cancer Institute
​3:20 - 3:40pm
BREAK
​3:40 - 3:50pm
Keyonote Speaker Introduction
TBA
KEYNOTE
3:50 - 4:40pm
Multiparameter functional diversity of human C2H2 zinc finger proteins
Timothy Hughes, PhD, University of Toronto
4:30 - 4:50pm
POSTER AWARDS
Gaylord Cary room
4:50 - 5:00pm
CLOSING REMARKS
ADJOURNMENT