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2016 SCHEDULE

FRIDAY, SEPTEMBER 23, 2016
Hohn Auditorium, Research Study Center, Roswell Park Cancer Institute

​8:00am

Registration - Breakfast

​8:45 - 9:00am

Welcome Remarks
Candace Johnson, PhD, CEO, Roswell Park Cancer Institute

SESSION I
METHYLATION AND HISTONE MODIFICATION
Session Chair: Dominic Smiraglia, PhD
Department Cancer Genetics, Roswell Park Cancer Institute

​9:00 - 9:05am

Session Introduction

​9:05 - 9:35am

Cis-acting control of DNA methylation

Paul Soloway, PhD, Cornell University

9:35 - 10:05am

Translocation Associated Sarcomas: Reprogramming the Cancer Epigenome

Joyce Ohm, PhD, Roswell Park Cancer Institute

10:05 - 10:35am

Control of cell differentiation by 5-hydroxymethylcytosine

Lucy Godley, MD, PhD, University of Chicago

​10:35 - 10:50am

DNA methylation profile in lungs of smokers and patients with COPD is associated with specific genes and cellular pathways

Isaac Sundar, University of Rochester

​10:50 - 11:00am

BREAK

​11:00 - 11:10am

Keyonote Speaker Introduction

Anna Woloszynska-Read, PhD, Roswell Park Cancer Institute

11:10 - 12:00pm

Transcriptional dynamics in epigenetic plasticity: implications for cancer biology and therapy

Paula Vertino, PhD, Emory University

KEYNOTE

12:00 - 1:30pm

LUNCH

POSTER SESSION 

Gaylord Cary room

-- opportunity to do a guided walking tour around campus organized by BNMC --

SESSION II
INTEGRATIVE GENOMICS
Session Chair: Irwin Gelman, PhD
Department of Cancer Genetics, Roswell Park Cancer Institute

1:30 - 1:35pm

Session Introduction

​1:35 - 2:05pm

Dissecting molecular mechanisms of transcription regulation in vivo using genome-wide strategies

John Lis, PhD, Cornell University

2:05 - 2:35pm

DNA variations at regulatory elements

Tao Liu (SUNY University at Buffalo)

2:35 - 3:05pm

The hitherto unknown RNA editing activity of APOBEC proteins

Santosh Patnaik, MD, PhD, Roswell Park Cancer Institute

3:05 - 3:20pm

Molecular dissection of the oncogenic role of ETS1 in basal subtypes of breast cancer

Christian Gluck, University of Buffalo

​3:20 - 3:40pm

BREAK

​3:40 - 3:50am

Keyonote Speaker Introduction

Michael Buck, PhD, SUNY University at Buffalo

3:50 - 4:40pm

Precision medicine: forgetting the germ line?

Charis Eng, PhD, Cleveland Clinic

KEYNOTE

4:40 - 6:00pm

SOCIAL GATHERING/POSTER SESSION, co-sponsored by RPCI and BNMC

Gaylord Cary room

SATURDAY, SEPTEMBER 24, 2016
Hohn Auditorium, Research Study Center, Roswell Park Cancer Institute

​8:00am

Registration - Breakfast

SESSION III
EPIGENOMICS THERAPY AND BIOMARKERS
Session Chair: James Jarvis, MD, Department of Pediatrics, SUNY University at Buffalo

​9:00 - 9:05am

Session Introduction

​9:05 - 9:35am

Epigenetics and the heart of malignancy

Yogen Saunthararajah, MD, Cleveland Clinic

9:35 - 10:05am

Arsenic, a genotoxic and/or epigenotoxic carcinogen?

Xuefeng Ren, MD, PhD, SUNY University at Buffalo

10:05 - 10:35am

Epigenomics in population studies to understand cancer etiology

Christine Ambrosone, PhD, Roswell Park Cancer Institute

​10:35 - 10:50am

Chromatin disruption with small molecule as a novel type of anti-cancer therapy

Katerina Gurova, PhD, Roswell Park Cancer Institute

​10:50 - 11:00am

BREAK

​11:00 - 11:10am

Keyonote Speaker Introduction

Prashant Singh, PhD, Roswell Park Cancer Institute

KEYNOTE

11:10 - 12:00pm

DNA Methylation as a Biomarker and Therapeutic Target in Cancer

David De Carvalho, PhD, Ontario Cancer Institute, Princess Margaret Hospital

12:00 - 1:30pm

LUNCH

POSTER SESSION 

Gaylord Cary room

SESSION IV
CLINICAL GENOMICS
Session Chair: Norma Nowak, PhD
Department of Biochemistry, SUNY University at Buffalo

1:30 - 1:35pm

Session Introduction

​1:35 - 2:05pm

A rational for targeting common features of cancer cells

Hartmut K. Land, PhD, University of Rochester

2:05 - 2:35pm

Precision medicine trials in oncology

Carl Morrison, MD, DVM, OmniSeq

2:35 - 3:05pm

Leveraging clinical genomics to enable personalized medicine prostate and multiple myeloma case studies

John Rushton, PhD, Empire Genomics

3:05 - 3:20pm

Off-target analysis of RNAI screens identifies microRNA contributing to metastatic invasion

Henry Withers, Roswell Park Cancer Institute

​3:20 - 3:40pm

BREAK

​3:40 - 3:50pm

Keyonote Speaker Introduction

TBA

KEYNOTE

3:50 - 4:40pm

Multiparameter functional diversity of human C2H2 zinc finger proteins

Timothy Hughes, PhD, University of Toronto

4:30 - 4:50pm

POSTER AWARDS

Gaylord Cary room

4:50 - 5:00pm

CLOSING REMARKS

 

ADJOURNMENT