4th Translational Genomics & Epigenomics Symposium
September 19 & 20, 2024
2017 SCHEDULE
THURSDAY, OCTOBER 12, 2017
Hohn Lecture Hall, Research Study Center, Roswell Park Cancer Institute
​8:00am
Registration - Breakfast
​8:45 - 9:00am
Welcome Remarks
Candace Johnson, PhD, CEO, Roswell Park Cancer Institute
SESSION I
SYSTEMS BIOLOGY
Session Chair: Martin Morgan, PhD
Department of Biostatistics and Bioinformatics/Bioconductor, Roswell Park Cancer Institute)
​9:00 - 9:05am
Session Introduction
​9:05 - 9:35am
Reactivation of super-enhancers by KLF4 in human head and neck squamous cell carcinoma
Michael Buck, PhD, State University of New York at Buffalo
9:35 - 10:05am
The HMGN chromatin architectural factors counteract H1 and remodel histone tail domains within nucleosomes
Jeffrey Hayes, PhD, University of Rochester Medical Center
10:05 - 10:35am
Reconstructing regulatory networks from bulk and scRNA-Seq data
Ziv Bar-Joseph, PhD, Carnegie Mellon University
​10:35 - 10:50am
In silico identification of metabolic dysregulation across cancer
Spencer Rosario, Roswell Park Cancer Institute
​10:50 - 11:30am
BREAK
​11:00 - 11:15am
Illumina, Kellie Harrington
Vendor talk - Pressman Conference room, 2nd floor room 232
​11:00 - 11:15am
Agena Bioscience, Ryan Birse
Vendor talk - HR Training Center, 2nd floor, room 255
​11:15 - 11:30am
Norgen Biotek, Bernard Lam
Vendor talk - Pressman Conference room, 2nd floor, 232
​11:15 - 11:30am
Agilent Technologies, Bridette Kipphut
Vendor talk - HR Training Center, 2nd floor, room 255
​11:30 - 11:35am
Keyonote Speaker Introduction
Richard Gronostajski, PhD, SUNY at Buffalo
KEYNOTE
11:35 - 12:30pm
Mapping a genetic wiring diagram of a cell
Brenda Andrews, PhD, CC FRSC, University of Toronto
12:30 - 1:30pm
LUNCH
Gaylord Cary room
SESSION II
FUNCTIONAL GENOMICS
Session Chair: Kirsten Moysich, PhD
Department of Cancer Prevention and Control, Roswell Park Cancer Institute
1:30 - 1:35pm
Session Introduction
​1:35 - 2:05pm
Cancer cell heterogeneity and therapy resistance
Dean Tang, PhD, Roswell Park Cancer Institute
2:05 - 2:35pm
Novel function of DNA methylation in gene 3' end
Angela Ting, PhD, Cleveland Clinic
2:35 - 3:05pm
REDfly adn SCRMshaw: powerful tools for functional genomics
Marc Halfon, PhD, State University or New York at Buffalo
3:05 - 3:20pm
Tet1 catalytic domain knocking-out impairs neural differentiation of human embryonic stem cells
Hanquin Li, SUNY at Buffalo
​3:20 - 4:00pm
BREAK
3:30 - 3:45pm
Fluidigm, Luke Stewart
Vendor talk - Pressman Conference room, 2nd floor, room 232
​3:30 - 3:45pm
ThermoFisher, Michael Christiaens
Vendor talk - HR Training Center, 2nd floor, room 255
3:45 - 4:00pm
Integrated DNA Technologies (IDT), Ryan Demeter
Vendor talk - Pressman Conference room, 2nd floor, room 232
​3:45 - 4:00pm
Nanostring, Kit Fuhrman
Vendor talk - HR Training Center, 2nd floor, room 255
​4:00 - 4:05am
Keyonote Speaker Introduction
Prashant Singh, PhD, Roswell Park Cancer Institute
4:05 - 5:00pm
Functional genomics via CRISPR-Cas: new approaches and new challenges
Prashant Mali, PhD, University of California at San Diego
KEYNOTE
5:00 - 7:00pm
SOCIAL GATHERING / POSTER SESSION, co-sponsored by RPCI and BNMC
Clinical Science Center (CSC), main lobby
FRIDAY, OCTOBER 13, 2017
Hohn Lecture Hall, Research Study Center, Roswell Park Cancer Institute
​8:00am
Registration - Breakfast
​8:45 - 9:00am
Welcome Remarks
Kunle Odunsi, MD, PhD, Deputy Director, Roswell Park Cancer Institute
SESSION III
TRANSLATIONAL GENOMICS
Session Chair: David Goodrich, PhD
Department of Pharmacology and Therapeutics, Roswell Park Cancer Institute
​9:00 - 9:05am
Session Introduction
​9:05 - 9:35am
Translational genomics for cutaneous autoimmunity
Aminesh Sinha, MD, PhD, State University of New York at Buffalo
9:35 - 10:05am
Clinical application of somatic mutations
Song Liu, PhD, Roswell Park Cancer Institute
10:05 - 10:35am
Chromatin modifier gene mutations in urothelial carcinoma
Byron Lee, MD, PhD, Cleveland Clinic
​10:35 - 10:50am
Elucidating the function of histone mono-methyltransferase Setd8 in human erythropoiesis
Tyler Couch, University of Rochester
​10:50 - 11:05am
BREAK
​11:05 - 11:10am
Keynote Speaker Introduction
Prashant Singh, PhD, Roswell Park Cancer Institute
KEYNOTE
11:10 - 12:00pm
Epigenetics in precision medicine
Jean Pierre Issa, MD, Temple University
12:00 - 1:00pm
LUNCH
POSTER SESSION
Gaylord Cary room
SESSION IV
IMMUNOGENOMICS
Session Chair: Pawel Kalinski, MD, PhD
Department of Medicine, Roswell Park Cancer Institute
1:00 - 1:05pm
Session Introduction
Pawel Kalinski, MD, PhD
​1:05 - 1:35pm
Rethinking optimal animal models in the immunotherapy era - Release the hounds!
Kristy Richards, PhD, MD, Cornell University
1:35 - 2:05pm
Next generation engineered T cell immunotherapies for cancer
Richard Koya, MD, PhD, Roswell Park Cancer Institute
2:05 - 2:35pm
Combined genetics-genomics approaches to rheumatic disease - what multi-dimensional genomics data can teach us
James Jarvis, MD, State University of New York at Buffalo
2:35 - 2:50pm
Immunogenomics for the development of personalized T cell therapy for ovarian cancer
Muzamil Y. Want, Roswell Park Cancer Institute
​2:50 - 3:05pm
BREAK
​3:05 - 3:10pm
Keyonote Speaker Introduction
Joyce Ohm, PhD, Roswell Park Cancer Institute
KEYNOTE
3:10 - 4:00pm
Can targeting the epigenome of cancer and immune cells enhance the efficacy of immune therapy?
Steven Baylin, PhD, Johns Hopkins University
4:00 - 4:15pm
POSTER AWARDS
Gaylord Cary room
4:15 - 4:30pm
CLOSING REMARKS
ADJOURNMENT